Addison's disease symptoms usually develop slowly, often over several months, and may include:
- Muscle weakness and fatigue
- Weight loss and decreased appetite
- Darkening of your skin (hyperpigmentation)
- Low blood pressure, even fainting
- Salt craving
- Low blood sugar (hypoglycemia)
- Nausea, diarrhea or vomiting
- Muscle or joint pains
- Irritability
- Depression
Acute adrenal failure (addisonian crisis)
Sometimes, however, the signs and symptoms of Addison's disease may appear suddenly. In acute adrenal failure (addisonian crisis), the signs and symptoms may also include:
- Pain in your lower back, abdomen or legs
- Severe vomiting and diarrhea, leading to dehydration
- Low blood pressure
- Loss of consciousness
- High potassium (hyperkalemia)
Common Cushing's syndrome symptoms include:
- Weight gain, particularly around your midsection and upper back
- Fatigue
- Muscle weakness
- Rounding of your face (moon face)
- Facial flushing
- Fatty pad or hump between your shoulders (buffalo hump)
- Pink or purple stretch marks (striae) on the skin of your abdomen, thighs, breasts and arms
- Thin and fragile skin that bruises easily
- Slow healing of cuts, insect bites and infections
- Depression, anxiety and irritability
- Loss of emotional control
- Thicker or more visible body and facial hair (hirsutism)
- Acne
- Irregular or absent menstrual periods in females
- Decreased libido
- Erectile dysfunction in males
- New or worsened high blood pressure
- Glucose intolerance that may lead to diabetes
- Headache
- Bone loss, leading to fractures over time
http://www.cushings-help.com/symptoms.htm
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